Does McAfee Total Protection run on Linux?

There is no McAfee Total Protection for Linux desktops. The Linux products from the same lineage belong to Trellix and are sold to businesses managing servers, not to people with a laptop.

The reason is simple enough. Nearly all the malware aimed at ordinary people is a Windows program, and a Windows program cannot run on Linux. Software on Linux comes from your system's app store rather than from download sites, and the whole machine updates through that same place, which closes off the most common way an infection arrives.

That is not the same as being safe from everything. A scam email, a fake login page and a password reused in twenty places all work exactly as well against you on Linux. Those are the risks worth spending your attention on, and none of them is solved by antivirus.

If your subscription still has time on it and you have a phone or tablet, check what your plan covers and keep using it there.

The one Linux scanner worth knowing about is ClamAV, and it is not a McAfee replacement. It exists to spot Windows malware in files, which is useful when you are forwarding an attachment to someone who is still on Windows.